MA pay to provider denials

Has anyone had any issues with MA and their billing location NPI dropping off claims and then MA denying? the NPI for the specific service provider locations seem to be dropping off the claims, resulting in multiple denials that we are manually fixing in MN-its.

Any feedback would be helpful. Thank you

We have put a ticket, but just aren't having any luck. Also have tired calling the state and there is no internal issues on their end.